LeanBiome (Now Sold as Biome) Review: What Is in It and Does It Work?

Disclosure: we may earn a commission if you buy LeanBiome (now sold as Biome) through links on this page. Last updated 29 October 2026. For the most up-to-date information, see the official Biome page at bestleanlife.com. The views expressed in this review are ours and do not represent the views or opinions of Lean for Good or the Biome brand.

LeanBiome Is Now Biome

The product we review here as LeanBiome is now sold as Biome by Lean for Good. Archived copies of the seller's sales page switch from "LeanBiome" to "Biome" between February and March 2025, and the old LeanBiome label, still on the seller's website, is identical to the Biome label apart from the name, so the formula did not change. The seller gives no reason for the rename. The checkout still runs through ClickBank under the "leanbiome" vendor name. Note that leanbiome.com belongs to a different company, which makes a prebiotic ingredient of that name; it is not this product's website.

What Is in It

The Supplement Facts panel on the seller's website lists, per two-capsule daily serving:

That is more disclosure than most products in this category: the label gives an amount for every ingredient and live-bacteria counts (CFU) for the two main species. The gaps are that seven of the nine species share one blend with no individual counts, and no strain codes are given for any of them.

The Claimed Mechanism

The vendor's theory centres on the make-up of the gut flora. Studies have found that lean and obese people tend to have different mixes of gut bacteria, but it is not clear whether this helps cause weight gain or results from diet and weight. A few specific probiotic strains have been tested in small trials for belly fat and weight, with modest results. Because the label gives no strain codes, it is not possible to confirm that Biome contains the strains that were tested. The vendor says it uses acid-resistant delayed-release capsules (DRcaps) to help the bacteria survive stomach acid. No data have been published on how many of Biome's bacteria reach the intestine alive.

The Probiotic Species

The two named species make up most of the formula: 10 billion CFU of L. gasseri and 5 billion of L. rhamnosus a day. Specific strains of these species have been tested in small trials: in Japan, the SBT2055 strain of L. gasseri modestly reduced belly fat over 12 weeks, an effect that faded after people stopped, while evidence for L. rhamnosus and weight is limited. The sales page also cites a 43-day trial of L. fermentum, one of seven species sharing just 5 billion CFU in the blend. The vendor claims these bacteria reduce cravings, but this has not been tested in Biome itself, and evidence for individual strains is limited. Gut bacteria may influence appetite signals, but it has not been shown that a probiotic supplement makes a diet easier to stick to.

Green Tea Phytosome

Biome also contains 300 mg of a green tea phytosome: decaffeinated green tea extract bound to phospholipids. The sales page calls it Greenselect Phytosome, a branded ingredient, although the label itself just says "Green Tea Phytosome". Its maker says the phospholipid form improves absorption. One small single-dose study from 1998, with authors from the maker, found the catechins were absorbed better in this form than as a standard extract; we found no larger independent studies. In human trials, green tea extract has had only small effects on weight, which a Cochrane review judged not clinically important. For Greenselect Phytosome itself, with a calorie-reduced diet, 300 mg a day (the amount in Biome) was linked to extra weight loss in one unblinded trial and better weight maintenance in another; it has not been tested together with these probiotics.

Sphaeranthus Indicus and Mangosteen

An earlier version of this review missed these two plant extracts, which are on the label: 300 mg of Sphaeranthus indicus, a herb used in Ayurvedic medicine, and 100 mg of mangosteen fruit rind (Garcinia mangostana, not to be confused with Garcinia cambogia). The same two plants make up Meratrim, a branded weight-loss ingredient. In small, short randomized trials, Meratrim at 800 mg a day (400 mg twice daily) led to about 4 to 5 kg more weight loss than placebo over 8 to 16 weeks, but everyone also ate a set 2,000-calorie diet and walked 30 minutes five days a week, and we found no independent replication. Biome provides 400 mg a day of the two herbs combined, half the dose used in those trials, and its label does not say whether it uses Meratrim or how the extracts are standardised. The sales page says the pair is "clinically shown in multiple studies" to reduce belly fat but cites none.

Inulin

The 200 mg of inulin is there to feed the bacteria, but it is a token amount: studies of inulin as a prebiotic used about 5 to 12 grams a day, 25 to 60 times as much (see our inulin page).

The Cravings Claim

One of the biggest hurdles in any weight management journey is the psychological and physiological battle with cravings. The vendor presents reduced hunger and cravings as a main benefit. Researchers are studying whether gut bacteria influence appetite hormones such as ghrelin and leptin, but this is not settled in people. The idea that sugar-loving gut bacteria trigger cravings to feed themselves is a hypothesis, not an effect proven in people. There is no published evidence that Biome reduces cravings for snacks and sweets.

What the Sales Page Says

The current sales page makes bigger claims than the published research supports. Its headline calls Biome "Nature's Ozempic"; it is a probiotic and herbal supplement, not a GLP-1 medicine, and no study shows it has a similar effect. It is built around a founder who says she lost 240 lb, plus testimonials with specific weight losses, none of which we can verify. It says you can lose weight without changing your diet or exercising, then recommends a healthy diet in its FAQ. It shows a "quantity remaining" counter and a countdown timer. Its text version says Biome should be "perfectly safe" in pregnancy and breastfeeding, while the bottle's label tells pregnant and nursing women to consult a doctor first; follow the label.

Price and Packages

The ClickBank sales page we link to has no single-bottle option: two bottles cost $158 ($79 each), three cost $207 ($69 each) and six cost $294 ($49 each), with $9.95 US shipping on the two- and three-bottle packages and free shipping on six. Lean for Good's own shop (leanforgood.com) lists lower prices for the same product: one bottle for $59, three for $147 and six for $234, plus 10% off for a subscription. Both check out through ClickBank. Each bottle holds 60 capsules, a 30-day supply. Prices checked on 13 October 2026.

Quality and Manufacturing Standards

The vendor says Biome is made in an FDA-inspected, GMP-certified facility in the United States and is third-party tested; the label names a distributor in Ohio but no manufacturer. We have not seen independent test results confirming its contents or CFU counts. The vendor says it is vegan and free from gluten, dairy, eggs, soy and nuts.

Taking It

The label says to take two delayed-release capsules a day; the sales page suggests the morning, before breakfast. Probiotics are meant to be taken daily; in the L. gasseri trials, the belly-fat reduction faded after people stopped. Trials of these species have run for about 10 to 24 weeks. The vendor recommends three- or six-month packages, saying the trials it cites took 90 days; we have no customer data on results. A diet rich in fibre and whole foods also feeds gut bacteria, whatever supplement you take.

Who Should Be Careful

The vendor targets people who feel they have hit a weight-loss plateau. Whether gut bacteria cause a plateau, and whether a probiotic can change that, has not been established. Probiotics and inulin can cause gas and bloating at first. The label tells pregnant or nursing women, under-18s and anyone with a medical condition to consult a doctor before taking it, and people who are immunocompromised or seriously ill should ask a doctor before taking any probiotic. Green tea extract can lower blood levels of some drugs, such as nadolol and atorvastatin, and safety data on Sphaeranthus and mangosteen extracts come mainly from the same short trials.

Realistic Expectations

We have no customer data, so we cannot say what results people typically get. Gas and bloating in the first weeks are common side effects of probiotics and inulin. Any supplement should support a healthy diet and activity, not replace them, whatever the sales page says.

Final Thoughts

Biome (formerly LeanBiome) discloses more about its formula than most weight-management supplements, and two of its ingredients have some trial evidence: green tea phytosome at the studied dose, and a Sphaeranthus and mangosteen blend at half the studied dose. Its probiotic strains cannot be matched to the trials, the inulin dose is token, and the combined formula has not been tested. Its sales page leans on "Nature's Ozempic" claims and urgency tactics. If you want to try it, compare the ClickBank price with the brand's own shop, and use the 180-day refund to judge it.